Article
Evaluation of a multiple peptide assay for typing of antibodies to the hepatitis C virus: relation to genomic typing by the polymerase chain reaction.
Journal of medical virology - 1 Jan 1995
Zhang Z X, Yun Z B, Chen M, Sönnerborg A, Sällberg M
Abstract excerpt
A panel of 16 type-specific synthetic peptides corresponding to variable antigenic regions within the hepatitis C virus (HCV) core, nonstructural 4 (NS4), and NS5 proteins was synthesised. The peptide panel was used to develop an enzyme immunoassay (EIA) for the detection of antibodies directed t...
Topics
- Amino Acid Sequence
- Antigens, Viral
- Cross Reactions
- Enzyme-Linked Immunosorbent Assay
- Genotype
- Hepacivirus
- Hepatitis Antibodies
- Hepatitis C Antibodies
- Humans
- Molecular Sequence Data
- Peptides
- Polymerase Chain Reaction
- RNA, Viral
- Sensitivity and Specificity
- Sequence Homology, Amino Acid
- Species Specificity
- Viral Core Proteins
- Viral Nonstructural Proteins