Article
Immunodominant regions within the hepatitis C virus core and putative matrix proteins.
Journal of clinical microbiology - 1 Aug 1992
Sällberg M, Rudén U, Wahren B, Magnius L O
Abstract excerpt
The complete amino acid sequences of hepatitis C virus (HCV) core (residues 1 to 115) and putative matrix (residues 116 to 190) proteins were synthesized as 18-residue-long peptides with an 8-amino-acid overlap. The peptides were assayed with 50 human serum samples with antibodies to HCV (anti-HCV) and 46 serum samples without anti-HCV, as determined by several commercial assays. Immunodominant regions were...
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