Article
Two distinct subtypes of hepatitis C virus defined by antibodies directed to the putative core protein.
Hepatology (Baltimore, Md.) - 1 Oct 1992
Machida A, Ohnuma H, Tsuda F, Munekata E, Tanaka T, Akahane Y, Okamoto H, Mishiro S
Abstract excerpt
Four distinct genotypes of hepatitis C virus types I, II, III and IV have been identified by comparison of nucleotide sequences of isolates from different areas of the world. We examined the possibility that hepatitis C virus may have serologically definable subtypes. Enzyme-linked immunosorbent assay systems were prepared by use of two synthetic peptides deduced from the putative core protein of hepatitis C...
Topics
- Amino Acid Sequence
- Enzyme-Linked Immunosorbent Assay
- Epitopes
- Genotype
- Hepacivirus
- Hepatitis Antibodies
- Hepatitis C
- Hepatitis C Antibodies
- Humans
- Molecular Sequence Data
- Serology