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Article

Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets.

Human molecular genetics - 1 May 2008

Sutton Beth S, Crosslin David R, Shah Svati H, Nelson Sarah C, Bassil Anthony, Hale A Brent, Haynes Carol, Goldschmidt-Clermont Pascal J, Vance Jeffery M, Seo David, Kraus William E, Gregory Simon G, Hauser Elizabeth R

Abstract excerpt

Platelet-activating factor acetylhydrolase (PLA2G7) is a potent pro- and anti-inflammatory molecule that has been implicated in multiple inflammatory disease processes, including cardiovascular disease. The goal of this study was to investigate the genetic effects of PLA2G7 on coronary artery disease (CAD) risk in two large, independent datasets with CAD. Using a haplotype tagging (ht) approach, 19 ht single...

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Identifiers

PMID: 18204052
DOI: 10.1093/hmg/ddn020
PMCID: PMC2652668

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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