Article

The CovR regulatory network drives the evolution of Group B <i>Streptococcus</i> virulence

2021-01-25

Abstract excerpt

<h4>ABSTRACT</h4> Virulence of the neonatal pathogen Group B Streptococcus depends on the master regulator CovR. Inactivation of CovR leads to large-scale transcriptome remodeling and impairs almost every step of the interaction between the pathogen and the host. However, comparative analyses suggested a plasticity of the CovR signalling pathway in clinical isolates, probably due to the host selective pressure a...

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Literature Corpus work: 0300d90e-ee70-5db3-a9e5-d143f8df3e6f
DOI: 10.1101/2021.01.25.428120

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