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Article

Sparse representation and Bayesian detection of genome copy number alterations from microarray data.

Bioinformatics (Oxford, England) - 1 Feb 2008

Pique-Regi Roger, Monso-Varona Jordi, Ortega Antonio, Seeger Robert C, Triche Timothy J, Asgharzadeh Shahab

Abstract excerpt

MOTIVATION: Genomic instability in cancer leads to abnormal genome copy number alterations (CNA) that are associated with the development and behavior of tumors. Advances in microarray technology have allowed for greater resolution in detection of DNA copy number changes (amplifications or deletions) across the genome. However, the increase in number of measured signals and accompanying noise from the array...

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Identifiers

PMID: 18203770
DOI: 10.1093/bioinformatics/btm601
PMCID: PMC2704547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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