Article
CARAT: a novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays.
BMC bioinformatics - 21 Feb 2006
Huang Jing, Wei Wen, Chen Joyce, Zhang Jane, Liu Guoying, Di Xiaojun, Mei Rui, Ishikawa Shumpei, Aburatani Hiroyuki, Jones Keith W, Shapero Michael H
Abstract excerpt
BACKGROUND: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterations can lead to gains in cellular oncogenes as well as losses in tumor suppressor genes and can span small intervals a...
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