Article
Genotypic resistance testing in HIV by arrayed primer extension.
Analytical and bioanalytical chemistry - 1 Jul 2008
Schanné Michaela, Bodem Jochen, Gerhold-Ay Aslihan, Jacob Anette, Fellenberg Kurt, Kräusslich Hans-Georg, Hoheisel Jörg D
Abstract excerpt
The analysis of mutations that are associated with the occurrence of drug resistance is important for monitoring the antiretroviral therapy of patients infected with human immunodeficiency virus (HIV). Here, we describe the establishment and successful application of Arrayed Primer Extension (APEX) for genotypic resistance testing in HIV as a rapid and economical alternative to standard sequencing. The assay is...
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