Article
Data-intensive analysis of HIV mutations.
BMC bioinformatics - 5 Feb 2015
Ozahata Mina Cintho, Sabino Ester Cerdeira, Diaz Ricardo Sobhie, Cesar Roberto M, Ferreira João Eduardo
Abstract excerpt
BACKGROUND: In this study, clustering was performed using a bitmap representation of HIV reverse transcriptase and protease sequences, to produce an unsupervised classification of HIV sequences. The classification will aid our understanding of the interactions between mutations and drug resistance. 10,229 HIV genomic sequences from the protease and reverse transcriptase regions of the pol gene and antiretroviral...
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