Article
Detection of human immunodeficiency virus type 1 antiretroviral resistance mutations by high-density DNA probe arrays.
Journal of clinical microbiology - 1 Jul 2004
Gonzalez R, Masquelier B, Fleury H, Lacroix B, Troesch A, Vernet G, Telles J N
Abstract excerpt
Genotypic resistance testing has become an important tool in the clinical management of patients infected with human immunodeficiency virus type 1 (HIV-1). Standard sequencing methodology and hybridization-based technology are the two principal methods used for HIV-1 genotyping. This report describes an evaluation of a new hybridization-based HIV-1 genotypic test of 99 clinical samples from patients infected...
Topics
- Anti-HIV Agents
- DNA Probes
- Drug Resistance, Viral
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Mutation
- Oligonucleotide Array Sequence Analysis
- Reverse Transcriptase Polymerase Chain Reaction