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Article

An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies.

PloS one - 1 Jan 2016

Martín Verónica, Perales Celia, Fernández-Algar María, Dos Santos Helena G, Garrido Patricia, Pernas María, Parro Víctor, Moreno Miguel, García-Pérez Javier, Alcamí José, Torán José Luis, Abia David, Domingo Esteban, Briones Carlos

Abstract excerpt

The response of human immunodeficiency virus type 1 (HIV-1) quasispecies to antiretroviral therapy is influenced by the ensemble of mutants that composes the evolving population. Low-abundance subpopulations within HIV-1 quasispecies may determine the viral response to the administered drug combinations. However, routine sequencing assays available to clinical laboratories do not recognize HIV-1 minority variants...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27959928
DOI: 10.1371/journal.pone.0166902
PMCID: PMC5154500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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