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Article

Parental effect of DNA (Cytosine-5) methyltransferase 1 on grandparental-origin-dependent transmission ratio distortion in mouse crosses and human families.

Genetics - 1 Jan 2008

Yang Lanjian, Andrade Moises Freitas, Labialle Stephane, Moussette Sanny, Geneau Geneviève, Sinnett Donna, Belisle Alexandre, Greenwood Celia M T, Naumova Anna K

Abstract excerpt

Transmission ratio distortion (TRD) is a deviation from the expected Mendelian 1:1 ratio of alleles transmitted from parents to offspring and may arise by different mechanisms. Earlier we described a grandparental-origin-dependent sex-of-offspring-specific TRD of maternal chromosome 12 alleles closely linked to an imprinted region and hypothesized that it resulted from imprint resetting errors in the maternal...

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Identifiers

PMID: 18202356
DOI: 10.1534/genetics.107.081562
PMCID: PMC2206083

Genes

TRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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