Article
From paramutation to human disease: RNA-mediated heredity.
Seminars in cell & developmental biology - 1 Aug 2015
Rassoulzadegan Minoo, Cuzin François
Abstract excerpt
Epigenetic variation, a stable alteration in gene expression, occurs at multiple moments during development. Several instances of non-Mendelian transmission to the progenies modes are very intriguing. Studies of the mode of hereditary transmission revealed in a series of such cases a role of noncoding RNA molecules as inducers. While still an enigmatic mechanism, emerging models pinpoint to a more general roles...
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