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Article

Inheritance patterns of maternal alleles in imprinted regions of the mouse genome at different stages of development.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2002

Croteau Sylvie, Andrade Moises Freitas, Huang Fleur, Greenwood Celia M T, Morgan Kenneth, Naumova Anna K

Abstract excerpt

Deviations from Mendelian 1:1 transmission ratio have been observed in mice and humans. With few exceptions, the mechanism leading to transmission-ratio distortion (TRD) remains obscure. We proposed that a genomic imprinting mechanism plays a key role in the genesis of grandparental origin-dependent TRD (Naumova et al. 2001). To further test this hypothesis, we analyzed the transmission of grandparental alleles...

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PMID: 11773965
DOI: 10.1007/s00335-001-2095-x

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TRD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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