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Article

Transmission ratio distortion: review of concept and implications for genetic association studies.

Human genetics - 1 Mar 2013

Huang Lam Opal, Labbe Aurélie, Infante-Rivard Claire

Abstract excerpt

Transmission ratio distortion (TRD) occurs when one of the two alleles from either parent is preferentially transmitted to the offspring. This leads to a statistical departure from the Mendelian law of inheritance, which states that each of the two parental alleles is transmitted to offspring with a probability of 0.5. A number of mechanisms are thought to induce TRD such as meiotic drive, gametic competition,...

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Source

Identifiers

PMID: 23242375
DOI: 10.1007/s00439-012-1257-0

Genes

TRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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