Article
Imprinting and deviation from Mendelian transmission ratios.
Genome - 1 Jun 2001
Naumova A K, Greenwood C M, Morgan K
Abstract excerpt
Deviations from a Mendelian 1:1 transmission ratio have been observed in human and mouse chromosomes. With few exceptions, the underlying mechanism of the transmission-ratio distortion remains obscure. We tested a hypothesis that grandparental-origin dependent transmission-ratio distortion is related to imprinting and possibly results from the loss of embryos which carry imprinted genes with imprinting marks that...
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