Article
The 5' arm of Kluyveromyces lactis telomerase RNA is critical for telomerase function.
Molecular and cellular biology - 1 Mar 2008
Kabaha Majdi M, Zhitomirsky Benny, Schwartz Irit, Tzfati Yehuda
Abstract excerpt
Telomerase is a ribonucleoprotein reverse transcriptase that copies a short template within its integral telomerase RNA moiety (TER) onto eukaryotic chromosome ends, thus compensating for incomplete replication and degradation. The highly divergent yeast TER is structured in three long arms, with a catalytic core at its center. A binding site for the protein Ku80 is conserved within the 5' arm of TER in...
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