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Identification and comparative analysis of telomerase RNAs from <i>Candida</i> species reveal conservation of functional elements

17 Feb 2009

Abstract excerpt

The RNA component of telomerase (telomerase RNA; TER) varies substantially both in sequence composition and size (from approximately 150 nucleotides [nt] to >1500 nt) across species. This dramatic divergence has hampered the identification of TER genes and a large-scale comparative analysis of TER sequences and structures among distantly related species. To identify by phylogenetic analysis conserved sequences...

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Share to RNA and protein synthesis mechanisms
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PMID: 19223441
DOI: 10.1261/rna.1194009

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