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Article

Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA.

Proceedings of the National Academy of Sciences of the United States of America - 20 Dec 2011

Yen Wei-Feng, Chico Lidia, Lei Ming, Lue Neal F

Abstract excerpt

The yeast telomerase regulatory protein Est3 is required for telomere maintenance in vivo, and shares intriguing structural and functional similarities with the mammalian telomeric protein TPP1. Here we report our physical and functional characterizations of Est3 homologues from Candida parapsilosis and Lodderomyces elongisporus, which bear unique N- and C-terminal tails in addition to a conserved central OB...

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Identifiers

PMID: 21685334
DOI: 10.1073/pnas.1017855108
PMCID: PMC3251127

Genes

TERT
TPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA.PMID 21685334Read ↗

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