Article
Thiopurine methyltransferase polymorphisms in a multiracial asian population and children with acute lymphoblastic leukemia.
Journal of pediatric hematology/oncology - 1 Jan 2000
Kham S K Y, Tan P L, Tay A H N, Heng C K, Yeoh A E J, Quah Thuan-Chong
Abstract excerpt
The purpose of this study was to determine the frequency of thiopurine methyltransferase (TPMT) polymorphisms in a multiracial Asian population and to assess its relevance in the management of childhood acute lymphoblastic leukemia (ALL). Six hundred unrelated cord blood samples from 200 Chinese, Malay, and Indian healthy newborns were collected at the National University Hospital, Singapore; an additional 100...
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