Article
Association of common genetic variants with lipid traits in the Indian population.
PloS one - 1 Jan 2014
Walia Gagandeep Kaur, Gupta Vipin, Aggarwal Aastha, Asghar Mohammad, Dudbridge Frank, Timpson Nicholas, Singh Nongmaithem Suraj, Kumar M Ravi, Kinra Sanjay, Prabhakaran Dorairaj, Reddy K Srinath, Chandak Giriraj Ratan, Smith George Davey, Ebrahim Shah
Abstract excerpt
Genome-wide association studies (GWAS) have been instrumental in identifying novel genetic variants associated with altered plasma lipid levels. However, these quantitative trait loci have not been tested in the Indian population, where there is a poorly understood and growing burden of cardiometabolic disorders. We present the association of six single nucleotide polymorphisms in 1671 sib pairs (3342 subjects)...
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