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Article

Mutations of T-cell epitopes in the hepatitis B virus surface gene in children with chronic infection and hepatocellular carcinoma.

The American journal of gastroenterology - 1 Apr 2008

Ni Yen-Hsuan, Chang Mei-Hwei, Hsu Hong-Yuan, Tung Yi-Ching, Chen Huey-Ling, Wang Kuan-Jan, Tsuei Daw-Jen, Young Ni-Chi

Abstract excerpt

BACKGROUND AND OBJECTIVES: Hepatitis B virus (HBV) infection induces an interaction of host immune responses against virus antigen-presenting hepatocytes. The emergence of mutants is a strategy through which the virus can escape host attacks and produce chronic infection. In this study, we aimed to investigate mutations of the human leukocyte antigen-A2-restricted T-cell epitope (TCE) in chronic HBV-infected...

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Identifiers

PMID: 18190649
DOI: 10.1111/j.1572-0241.2007.01727.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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