Article
Different hepatitis B virus core gene mutations in children with chronic infection and hepatocellular carcinoma.
Gut - 1 Jan 2003
Ni Y-H, Chang M-H, Hsu H-Y, Tsuei D-J
Abstract excerpt
BACKGROUND: The significance of mutations of hepatitis B virus (HBV) precore/core antigen in causing persistent infection and subsequent liver diseases is debatable. AIM: To investigate HBV core gene sequence changes in children with chronic HBV infection and their implications in hepatocellular carcinoma (HCC). METHODS: Thirty one chronic HBV infected children with documented hepatitis B e antigen seroconversion...
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