Article
Naturally occurring hepatitis B surface gene variants in chronic hepatitis B virus infection: correlation with viral serotypes and clinical stages of liver disease.
Journal of medical virology - 1 Sept 2002
Liu Chun-Jen, Kao Jia-Horng, Shau Wen-Yi, Chen Pei-Jer, Lai Ming-Yang, Chen Ding-Shinn
Abstract excerpt
Virus variants escaping from host immunity may be implicated in the pathogenesis of hepatitis B virus (HBV) infection. In this cross-sectional study, the association was evaluated of the frequency of amino acid variation within the immunogenic epitopes of surface gene with different disease stages of chronic HBV infection. The surface gene of HBV encompassing the a determinant (amino acids 124-148) and the...
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