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Circulating HBV RNA and HBsAg seroconversion in patients with chronic HBV infection: a long-term follow-up study starting from childhood in Taiwan.

Gut - 8 Jul 2026

Wu Jia-Feng, Hsu Chien-Ting, Tai Chi-San, Chang Kai-Chi, Chu Chieh-Yu, Chiu Yu-Chun, Chen Huey-Ling, Ni Yen-Hsuan, Chang Mei-Hwei

Abstract excerpt

BACKGROUND: HBV surface antigen (HBsAg) seroconversion indicates the clearance of HBV in patients with chronic HBV infection. OBJECTIVE: We aimed to investigate the predictive value of HBV RNA and HBV mutants on HBsAg seroconversion in patients with chronic HBV infection from childhood to adulthood. DESIGN: We recruited 700 children (409 males and 291 females) with initially hepatitis B e antigen (HBeAg)-positive...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41419305
DOI: 10.1136/gutjnl-2025-337123

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