Article
A genetic variation in inositol polyphosphate 4 phosphatase a enhances susceptibility to asthma.
American journal of respiratory and critical care medicine - 1 Apr 2008
Sharma Mamta, Batra Jyotsna, Mabalirajan Ulaganathan, Sharma Shilpy, Nagarkatti Rana, Aich Jyotirmoi, Sharma Surendra K, Niphadkar Pramod V, Ghosh Balaram
Abstract excerpt
RATIONALE: Microarray data from mouse studies have identified a number of genes to be differentially expressed in allergen-sensitized mice lungs. OBJECTIVES: Taking leads from these datasets, we attempted to identify novel genes associated with atopic asthma in humans. METHODS: We performed family-based genetic association analysis on selected markers within or in proximity of 21 human homologs of genes...
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