Article
Relevance and implication of genetic determinants to asthma pathophysiology.
Current opinion in allergy and clinical immunology - 1 Oct 2011
Poon Audrey, Litonjua Augusto A, Laprise Catherine
Abstract excerpt
PURPOSE OF REVIEW: The number of single nucleotide polymorphisms (SNPs) found to be associated with asthma and related phenotypes outnumbers those with functional impacts. In this review we briefly described some of the approaches used to investigate functionality of SNPs, and summarized recent findings related to the characterization of functional SNPs in asthma. RECENT FINDINGS: For disease-associated SNPs...
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