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Mutations in the glucokinase gene of the fetus result in reduced placental weight.

Diabetes care - 1 Apr 2008

Shields Beverley M, Spyer Gill, Slingerland Annabelle S, Knight Bridget A, Ellard Sian, Clark Penelope M, Hauguel-de Mouzon Sylvie, Hattersley Andrew T

Abstract excerpt

OBJECTIVE: In human pregnancy, placental weight is strongly associated with birth weight. It is uncertain whether there is regulation of the placenta by the fetus or vice versa. We aimed to test the hypothesis that placental growth is mediated, either directly or indirectly, by fetal insulin. RESEARCH DESIGN AND METHODS: Birth weight and placental weight were measured in 43 offspring of 21 parents with mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18184897
DOI: 10.2337/dc07-1750

Genes

GCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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