Article
A significant association between BDNF promoter methylation and the risk of drug addiction.
Gene - 10 Jun 2016
Xu Xuting, Ji Huihui, Liu Guili, Wang Qinwen, Liu Huifen, Shen Wenwen, Li Longhui, Xie Xiaohu, Zhou Wenhua, Duan Shiwei
Abstract excerpt
As a member of the neurotrophic factor family, brain derived neurotrophic factor (BDNF) plays an important role in the survival and differentiation of neurons. The aim of our work was to evaluate the role of BDNF promoter methylation in drug addiction. A total of 60 drug abusers (30 heroin and 30 methylamphetamine addicts) and 52 healthy age- and gender-matched controls were recruited for the current case control...
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