Article
BDNF Val(66)Met genotype is associated with drug-seeking phenotypes in heroin-dependent individuals: a pilot study.
Addiction biology - 1 Sept 2013
Greenwald Mark K, Steinmiller Caren L, Sliwerska Elzbieta, Lundahl Leslie, Burmeister Margit
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) Val(66)Met genotype has been associated with neurobehavioral deficits. To examine its relevance for addiction, we examined BDNF genotype differences in drug-seeking behavior. Heroin-dependent volunteers (n = 128) completed an interview that assessed past-month naturalistic drug-seeking/use behaviors. In African Americans (n = 74), the Met allele was uncommon (carrier...
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