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Article

A118g polymorphism in mu opioid receptor gene (oprm1): association with opiate addiction in subjects of Indian origin.

Journal of integrative neuroscience - 1 Dec 2007

Kapur Suman, Sharad Shashwat, Singh R A, Gupta A K

Abstract excerpt

The opioidergic hypothesis suggests an association between genetic variations at the opioid receptor mu 1 (OPRM1) gene locus and opiate addiction. The OPRM1 gene, which encodes for mu opioid receptor, contains several single nucleotide polymorphisms (SNPs) in exon I. Two of these, C17T and A118G, have been reported to be associated with substance abuse. The present study aims to delineate the frequency of these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18181266
DOI: 10.1142/s0219635207001635

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A118g polymorphism in mu opioid receptor gene (oprm1): association with opiate addiction in subjects of Indian origin.PMID 18181266Read ↗

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Genotyping the Mu-opioid receptor A118G polymorphism using the real-time amplification refractory mutation system: allele frequency distribution among Brazilians.Semantic proximity Read ↗

Single-nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu-opioid receptor and may contribute to the genetic risk for addiction.Semantic proximity Read ↗

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