Article
Mu opioid receptor gene polymorphisms and heroin dependence in Asian populations.
Neuroreport - 24 Mar 2003
Tan Ene-Choo, Tan Chay-Hoon, Karupathivan Umavathy, Yap Eric P H
Abstract excerpt
The distribution of three polymorphisms of the mu opioid receptor gene (OPRM1) was investigated in four different Asian populations, and in heroin-dependent subjects deriving from three of these populations. For the A118G polymorphism, we found significant differences in allele and genotype frequencies between different ethnic groups and highly significant association with heroin dependence in Indians for both...
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