Article
Preliminary computational modeling of nitric oxide synthase 3 interactions with caveolin-1: influence of exon 7 Glu298Asp polymorphism.
Acta biochimica et biophysica Sinica - 1 Jan 2008
Joshi Mandar S, Bauer John Anthony
Abstract excerpt
The significance of endothelial nitric oxide synthase 3 (NOS3) activity has been recognized for many years, however it was only recently that the complicated regulation of this constitutively expressed enzyme in endothelial cells was identified. A critical component of the NOS3 regulatory cycle in endothelial cells is its intracellular localization to caveolae. The caveolar coordination of NOS3, more specifically...
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