Article
Three endothelial nitric oxide (NOS3) gene polymorphisms in hypertensive and normotensive individuals: meta-analysis of 53 studies reveals evidence of publication bias.
Journal of hypertension - 1 Sept 2007
Pereira Tiago V, Rudnicki Martina, Cheung Bernard M Y, Baum Larry, Yamada Yoshiji, Oliveira Paulo S L, Pereira Alexandre C, Krieger José E
Abstract excerpt
BACKGROUND: Studies on the relationship between endothelial nitric oxide (NOS3) gene variants and hypertension have been conflicting. To explore this hypothesis further, we performed a meta-analysis and re-evaluated the relationship between the three most widely studied NOS3 polymorphisms and hypertension status and blood pressure levels. METHODS: Data on 40,413 subjects from 53 studies were combined in five...
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