Article
Vertical hepatitis C virus transmission is not related to mother-child class-1 HLA concordance.
International journal of immunopathology and pharmacology - 1 Jan 2000
Azzari C, Indolfi G, Betti L, Moriondo M, Massai C, Becciolini L, Bertelli L, Poggi G M, De Martino M, Resti M
Abstract excerpt
Mother-child human leukocyte antigen (HLA)diversity is protective for vertical transmission of some viruses. The aim of this study is to evaluate the role of mother-child HLA diversity on hepatitis C virus (HCV) vertical transmission. Forty consecutive HCV infected and 46 consecutive control uninfected children born to HCV-RNA positive mothers were evaluated for HLA class-1 type concordance with their mothers. No...
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