Article
Maternal and child human leukocyte antigens in congenital cytomegalovirus infection.
Journal of reproductive immunology - 1 Apr 2018
Rovito Roberta, Claas Frans H J, Haasnoot Geert W, Roelen Dave L, Kroes Aloys C M, Vossen Ann C T M
Abstract excerpt
Congenital Cytomegalovirus infection (cCMV) is the most common cause of congenital infections worldwide causing permanent long-term impairment (LTI). cCMV immunopathogenesis remains largely unknown due to the complex interplay between viral, maternal, placental and child factors. The aim of this study was to determine the possible role of particular HLA antigens, of the number of HLA mismatches (mm) and...
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