Article
Mother‐Child Class I HLA Concordance Increases Perinatal Human Immunodeficiency Virus Type 1 Transmission
1 Mar 1998
Abstract excerpt
Major histocompatibility complex (MHC) gene products are expressed on human immunodeficiency virus (HIV)-infected cells and incorporated into the lipid envelope of HIV virions. Macaques immunized with human MHC gene products are protected from simian immunodeficiency virus challenge when the virus is grown in cells expressing the same MHC alleles. To relate these findings to mother-to-child transmission of HIV-1,...
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