Article
Association between maternal and infant class I and II HLA alleles and of their concordance with the risk of perinatal HIV type 1 transmission.
AIDS research and human retroviruses - 20 Jul 2002
Polycarpou Anastasia, Ntais Christos, Korber Bette T, Elrich Henry A, Winchester Robert, Krogstad Paul, Wolinsky Steven, Rostron Timothy, Rowland-Jones Sarah L, Ammann Arthur J, Ioannidis John P A
Abstract excerpt
We aimed to investigate the influence of class I and class II HLA specificities and of the concordance between maternal and infant HLA on vertical HIV-1 transmission. HLA typing of samples from mothers and infants enrolled in the Ariel study, a perinatal HIV-1 transmission cohort including 203 mother-infant pairs, was performed by serological and molecular methods. HLA effects were evaluated alone and by...
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