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Article

Kindlin-2 is an essential component of intercalated discs and is required for vertebrate cardiac structure and function.

Circulation research - 29 Feb 2008

Dowling James J, Gibbs Elizabeth, Russell Mark, Goldman Daniel, Minarcik Jeremy, Golden Jeffrey A, Feldman Eva L

Abstract excerpt

Integrins and proteins that associate with integrins are implicated in normal cardiac muscle function and development. Unc-112 is a cytoplasmic adaptor protein required for the proper establishment of integrin junctions in Caenorhabditis elegans muscle. A vertebrate homolog of unc-112, kindlin-2,...

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Identifiers

PMID: 18174465
DOI: 10.1161/CIRCRESAHA.107.161489

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18174465-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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