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Article

Kindling the flame of integrin activation and function with kindlins

13 Aug 2009

Abstract excerpt

PURPOSE OF REVIEW: There are three kindlin family members in vertebrates, which have high-sequence homology and a common organization signature with a C-terminal 4.1, ezrin, radixin, moesin (FERM) domain bisected by a pleckstrin-homology domain. Although the cell and tissue distributions of the three kindlins differ, there is a consistent and close interrelationship between kindlins and integrins, and alterations...

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PMID: 19553810
DOI: 10.1097/moh.0b013e32832ea389

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