Article
The calcium channel beta2 (CACNB2) subunit repertoire in teleosts.
BMC molecular biology - 17 Apr 2008
Ebert Alicia M, McAnelly Catherine A, Srinivasan Ashok, Mueller Rachel Lockridge, Garrity David B, Garrity Deborah M
Abstract excerpt
BACKGROUND: Cardiomyocyte contraction is initiated by influx of extracellular calcium through voltage-gated calcium channels. These oligomeric channels utilize auxiliary beta subunits to chaperone the pore-forming alpha subunit to the plasma membrane, and to modulate channel electrophysiology 1. Several beta subunit family members are detected by RT-PCR in the embryonic heart. Null mutations in mouse beta2, but...
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