Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The novel transmembrane protein Tmem2 is essential for coordination of myocardial and endocardial morphogenesis.

Development (Cambridge, England) - 1 Oct 2011

Totong Ronald, Schell Thomas, Lescroart Fabienne, Ryckebüsch Lucile, Lin Yi-Fan, Zygmunt Tomasz, Herwig Lukas, Krudewig Alice, Gershoony Dafna, Belting Heinz-Georg, Affolter Markus, Torres-Vázquez Jesús, Yelon Deborah

Abstract excerpt

Coordination between adjacent tissues plays a crucial role during the morphogenesis of developing organs. In the embryonic heart, two tissues - the myocardium and the endocardium - are closely juxtaposed throughout their development. Myocardial and endocardial cells originate in neighboring regions of the lateral mesoderm, migrate medially in a synchronized fashion, collaborate to create concentric layers of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endocardium
Share to Heart

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization

Share to Morphogenesis

Share to Myocardium

Share to Tissue Distribution

Share to Transgenes

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21896630
DOI: 10.1242/dev.064261
PMCID: PMC3171221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The novel transmembrane protein Tmem2 is essential for coordination of myocardial and endocardial morphogenesis.PMID 21896630Read ↗

Transmembrane protein 2 (Tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion development.Semantic proximity Read ↗

Myocardium and BMP signaling are required for endocardial differentiation.Semantic proximity Read ↗

Endoderm convergence controls subduction of the myocardial precursors during heart-tube formationSemantic proximity Read ↗

Hand2 ensures an appropriate environment for cardiac fusion by limiting Fibronectin function.Semantic proximity Read ↗

Lem2 is essential for cardiac development by maintaining nuclear integritySemantic proximity Read ↗

Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning.Semantic proximity Read ↗

Integrin α5 and Integrin α4 cooperate to promote endocardial differentiation and heart morphogenesis.Semantic proximity Read ↗

Fibronectin regulates epithelial organization during myocardial migration in zebrafish.Semantic proximity Read ↗

Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafishSemantic proximity Read ↗

Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle.Semantic proximity Read ↗

Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturitySemantic proximity Read ↗

Functional heterogeneity within the developing zebrafish epicardiumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.