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Article

Hypocholesterolemic effects of fatty acid bile acid conjugates (FABACs) in mice.

Archives of biochemistry and biophysics - 1 Mar 2008

Leikin-Frenkel Alicia, Parini Paolo, Konikoff Fred M, Benthin Lisbet, Leikin-Gobbi Diana, Goldiner Ilana, Einarsson Curt, Gilat Tuvia

Abstract excerpt

Fatty acid bile acid conjugates (FABACs) prevent and dissolve cholesterol gallstones and prevent diet induced fatty liver, in mice. The present studies aimed to test their hypocholesterolemic effects in mice. Gallstone susceptible (C57L/J) mice, on high fat (HFD) or regular diet (RD), were treated with the conjugate of cholic acid with arachidic acid (FABAC; Aramchol). FABAC reduced the elevated plasma...

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Identifiers

PMID: 18167305
DOI: 10.1016/j.abb.2007.12.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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