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Article

Impaired cholesterol metabolism in the mouse model of cystic fibrosis. A preliminary study.

PloS one - 1 Jan 2021

Amato Felice, Castaldo Alice, Castaldo Giuseppe, Cernera Gustavo, Corso Gaetano, Ferrari Eleonora, Gelzo Monica, Monzani Romina, Villella Valeria Rachela, Raia Valeria

Abstract excerpt

This study aims to investigate cholesterol metabolism in a mouse model with cystic fibrosis (CF) by the comparison of affected homozygous versus wild type (WT) mice. In particular, we evaluated the effects of a diet enriched with cholesterol in both mice groups in comparison with the normal diet. To this purpose, beyond serum and liver cholesterol, we analyzed serum phytosterols as indirect markers of intestinal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33412572
DOI: 10.1371/journal.pone.0245302
PMCID: PMC7790534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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