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Optimization of the cholesterol gallstone model in C57BL/6 mice and evaluation of Lactobacillus intervention effects

5 Feb 2025

Abstract excerpt

Gallstone disease is a common and complex condition, strongly associated with abnormal cholesterol metabolism, changes in bile composition, and impaired gallbladder motility. Recent studies have suggested that the gut microbiota, particularly probiotics like lactic acid bacteria, may play a significant role in the prevention and treatment of cholesterol gallstones. This study aims to optimize the cholesterol...

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PMID: 39910449
DOI: 10.1186/s12876-025-03653-0

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