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Article

Hip, an HP1-interacting protein, is a haplo- and triplo-suppressor of position effect variegation.

Proceedings of the National Academy of Sciences of the United States of America - 8 Jan 2008

Schwendemann Alexander, Matkovic Tanja, Linke Christian, Klebes Ansgar, Hofmann Annemarie, Korge Günter

Abstract excerpt

The Drosophila heterochromatin protein 1 (HP1) regulates epigenetic gene silencing and heterochromatin formation by promoting and maintaining chromatin condensation. Here we report the identification and characterization of an HP1-interacting protein (Hip). Hip interacts with HP1 in vitro and is associated with HP1 in vivo. This interaction is mediated by at least three independent but similar HP1-binding modules...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18162556
DOI: 10.1073/pnas.0705595105
PMCID: PMC2224187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hip, an HP1-interacting protein, is a haplo- and triplo-suppressor of position effect variegation.PMID 18162556Read ↗

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