Article
Drosophila DDP1, a multi-KH-domain protein, contributes to centromeric silencing and chromosome segregation.
Current biology : CB - 21 Sept 2004
Huertas Dori, Cortés Alfred, Casanova Jordi, Azorín Fernando
Abstract excerpt
BACKGROUND: The Drosophila melanogaster DDP1 protein is a highly evolutionarily conserved protein that is characterised by the presence of 15 tandemly organized KH domains, known for mediating high-affinity binding to single-stranded nucleic acids (RNA and ssDNA). Consistent with its molecular organization, DDP1 binds single-stranded nucleic acids with high affinity, in vitro. It was shown earlier that, in...
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