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Article

Genetic mediators of neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Jun 2013

Krull Kevin R, Bhojwani Deepa, Conklin Heather M, Pei Deqing, Cheng Cheng, Reddick Wilburn E, Sandlund John T, Pui Ching-Hon

Abstract excerpt

PURPOSE: Survivors of childhood acute lymphoblastic leukemia (ALL) are at increased risk for neurocognitive problems, with significant interindividual variability in outcome. This study examined genetic polymorphisms associated with variability in neurocognitive outcome. PATIENTS AND METHODS: Neurocognitive outcomes were evaluated at the end of therapy in 243 survivors treated on an institutional protocol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23650422
DOI: 10.1200/JCO.2012.46.7944
PMCID: PMC3731978

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