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Article

CLC Cl /H+ transporters constrained by covalent cross-linking.

Proceedings of the National Academy of Sciences of the United States of America - 26 Dec 2007

Nguitragool Wang, Miller Christopher

Abstract excerpt

CLC Cl(-)/H(+) exchangers are homodimers with Cl(-)-binding and H(+)-coupling residues contained within each subunit. It is not known whether the transport mechanism requires conformational rearrangement between subunits or whether each subunit operates as a separate exchanger. We designed variou...

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Identifiers

PMID: 18093952
DOI: 10.1073/pnas.0708639104
PMCID: PMC2409211

Genes

CLC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18093952-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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