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Article

Site-directed fluorescence studies of a prokaryotic ClC antiporter.

Biochemistry - 6 Jun 2006

Bell Susan P, Curran Patricia K, Choi Sean, Mindell Joseph A

Abstract excerpt

Channels and transporters of the ClC family serve a variety of physiological functions. Understanding of their gating and transport mechanisms remains incomplete, with disagreement over the extent of protein conformational change involved. Using site-directed fluorescence labeling, we probe ClC-ec1, a prokaryotic ClC, for transport-related structural rearrangements. We specifically label cysteines introduced at...

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Identifiers

PMID: 16734414
DOI: 10.1021/bi0523815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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